PS-liposome technology of Tolerogenics
Tolerogenics S.à.r.l. utilizes hydrogel-embedded PS-liposomes. This technology provides a sustained release of embedded PS-liposomes over a time period of at least 3 days, enabling high local concentration and efficient interaction with peripheral APCs, including dendritic cells and macrophages.
By combination of hydrogelembedded PS-liposomes with hydroge-embedded allergens or autoantigen, the sustained release of both components allows efficient tolorogenic priming of allergen/autoantigen-specific APCs and susequent enhancement of tolerance-promoting Tregs.